RNase A is an endoribonuclease that specifically cleaves single strand RNA from ends C and U. It separates the phosphodiester bond between the 5’-ribose of a nucleotide and the phosphate group bound to the 3‘ ribose of an adjacent pyrimidine nucleotide.
• Plasmid and genomic DNA preparation
• RNA removal from recombinant protein samples.
• Ribonuclease protection experiments
• Mapping of single base mutations in DNA or RNA
13.7 kDa monomer